Microglia and Aging: The Role of the TREM2–DAP12 and CX3CL1-CX3CR1 Axes

Depending on the species, microglial cells represent 5–20% of glial cells in the adult brain. As the innate immune effector of the brain, microglia are involved in several functions: regulation of inflammation, synaptic connectivity, programmed cell death, wiring and circuitry formation, phagocytosi...

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Bibliographic Details
Main Authors: Carmen Mecca, Ileana Giambanco, Rosario Donato, Cataldo Arcuri
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/19/1/318