Non-Linear Effects in the Formation of DNA Damage in Medaka Fish Fibroblast Cells Caused by Combined Action of Cadmium and Ionizing Radiation
Ionizing radiation-induced formation of genomic DNA damage can be modulated by nearby chemical species such as heavy metal ions, which can lead to non-linear dose response. To investigate this phenomenon, we studied cell survival and formation of 8-hydroxyguanine (8-OHG) base modifications and doubl...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2008-07-01
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| Series: | Dose-Response |
| Online Access: | https://doi.org/10.2203/dose-response.07-012.Grygoryev |