Saliva-Derived Host Defense Peptides Histatin1 and LL-37 Increase Secretion of Antimicrobial Skin and Oral Mucosa Chemokine CCL20 in an IL-1α-Independent Manner

Even though skin and oral mucosae are continuously in contact with commensal and opportunistic microorganisms, they generally remain healthy and uninflamed. Host defense peptides (HDPs) make up the body’s first line of defense against many invading pathogens and are involved in the orchestration of...

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Bibliographic Details
Main Authors: Mireille A. Boink, Sanne Roffel, Kamran Nazmi, Jan G. M. Bolscher, Enno C. I. Veerman, Susan Gibbs
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2017/3078194