Osteopontin and LDLR Are Upregulated in Hearts of Sudden Cardiac Death Victims With Heart Failure With Preserved Ejection Fraction and Diabetes Mellitus

Osteopontin and LDLR Are Upregulated in Hearts of Sudden Cardiac Death Victims With Heart Failure With Preserved Ejection Fraction and Diabetes Mellitus

Background: Diabetes mellitus (DM) is associated with increased risk of sudden cardiac death (SCD), particularly in patients with heart failure with preserved ejection fraction (HFpEF). However, there are no known biomarkers in the population with DM and HFpEF to predict SCD risk.Objectives: This st...

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Bibliographic Details
Main Authors: Mausam Patel, Daniela Rodriguez, Keyvan Yousefi, Krista John-Williams, Armando J. Mendez, Ronald B. Goldberg, Anastasios Lymperopoulos, Leonardo J. Tamariz, Jeffrey J. Goldberger, Robert J. Myerburg, Juhani Junttila, Lina A. Shehadeh
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
sudden cardiac death (SCD)
diabetes mellilus
osteopontin (OPN)
LDLR
HFpEF—heart failure with preserved ejection fraction
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2020.610282/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2020.610282/full

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