Serum Levels of TNF Receptor Ligands Are Dysregulated in Sepsis and Predict Mortality in Critically Ill Patients.

TNF superfamily members, including TNF-related weak inducer of apoptosis (TWEAK) and Glucocorticoid-Induced TNFR-Related Protein Ligand (GITRL) have been described as serum based biomarkers for inflammatory and immune mediated diseases. However, up to now the role of TWEAK and GITRL has not been ana...

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Bibliographic Details
Main Authors: Christoph Roderburg, Fabian Benz, Florian Schüller, Ines Pombeiro, Hans-Joerg Hippe, Norbert Frey, Christian Trautwein, Tom Luedde, Alexander Koch, Frank Tacke, Mark Luedde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4849634?pdf=render