p113 isoform encoded by CUX1 circular RNA drives tumor progression via facilitating ZRF1/BRD4 transactivation

p113 isoform encoded by CUX1 circular RNA drives tumor progression via facilitating ZRF1/BRD4 transactivation

Abstract Background Metabolic reprogramming sustains tumorigenesis and aggressiveness of neuroblastoma (NB), the most common extracranial malignancy in childhood, while underlying mechanisms and therapeutic approaches still remain elusive. Methods Circular RNAs (circRNAs) were validated by Sanger se...

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Bibliographic Details
Main Authors: Feng Yang, Anpei Hu, Yanhua Guo, Jianqun Wang, Dan Li, Xiaojing Wang, Shikai Jin, Boling Yuan, Shuang Cai, Yi Zhou, Qilan Li, Guo Chen, Haiyang Gao, Liduan Zheng, Qiangsong Tong
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Molecular Cancer
Subjects:
Circular RNA-coding protein
Zuotin-related factor 1
Bromodomain protein 4
Neuroblastoma progression
Online Access:https://doi.org/10.1186/s12943-021-01421-8

Internet

https://doi.org/10.1186/s12943-021-01421-8

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