Cellular and molecular characterization of multiplex autism in human induced pluripotent stem cell-derived neurons

Abstract Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder with pronounced heritability in the general population. This is largely attributable to the effects of polygenic susceptibility, with inherited liability exhibiting distinct sex differences in phenotypic expression....

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Bibliographic Details
Main Authors: Emily M. A. Lewis, Kesavan Meganathan, Dustin Baldridge, Paul Gontarz, Bo Zhang, Azad Bonni, John N. Constantino, Kristen L. Kroll
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Molecular Autism
Subjects:
Online Access:https://doi.org/10.1186/s13229-019-0306-0