Direct Characterization of Transcription Elongation by RNA Polymerase I.

RNA polymerase I (Pol I) transcribes ribosomal DNA and is responsible for more than 60% of transcription in a growing cell. Despite this fundamental role that directly impacts cell growth and proliferation, the kinetics of transcription by Pol I are poorly understood. This study provides direct char...

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Bibliographic Details
Main Authors: Suleyman Ucuncuoglu, Krysta L Engel, Prashant K Purohit, David D Dunlap, David A Schneider, Laura Finzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4959687?pdf=render