Circulating Levels of sFlt1 Splice Variants as Predictive Markers for the Development of Preeclampsia

Circulating Levels of sFlt1 Splice Variants as Predictive Markers for the Development of Preeclampsia

Angiogenic biomarkers, including soluble fms-like tyrosine kinase 1 (sFlt1), are thought to be predictors of preeclampsia onset; however, improvement is needed before a widespread diagnostic test can be utilized. Here we describe the development and use of diagnostic monoclonal antibodies specific...

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Bibliographic Details
Main Authors: Colby A. Souders, Sharon E. Maynard, Jing Yan, Yang Wang, Naomi K. Boatright, Jessica Sedan, David Balyozian, Peter S. Cheslock, Deborah C. Molrine, Tiffany A. Moore Simas
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:International Journal of Molecular Sciences
Subjects:
preeclampsia
soluble fms-like tyrosine kinase 1 (sFlt1)
splice variants
isoforms
monoclonal antibody (mAb)
diagnostic
Online Access:http://www.mdpi.com/1422-0067/16/6/12436

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http://www.mdpi.com/1422-0067/16/6/12436

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