Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans

Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans

The human meningitis fungal pathogen, Cryptococcus neoformans, contains the atypical yeast AP-1-like protein Yap1. Yap1 lacks an N-terminal cysteine-rich domain (n-CRD), which is present in other fungal Yap1 orthologs, but has a C-terminal cysteine-rich domain (c-CRD). However, the role of c-CRD and...

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Bibliographic Details
Main Authors: Yee-Seul So, Shinae Maeng, Dong-Hoon Yang, Hyelim Kim, Kyung-Tae Lee, Seong-Ryong Yu, Jennifer L. Tenor, Vinay K. Giri, Dena L. Toffaletti, Samantha Arras, James A. Fraser, John R. Perfect, Yong-Sun Bahn
Format: Article
Language:English
Published: American Society for Microbiology 2019-11-01
Series:mSphere
Subjects:
ap-1-like transcription factor
c. neoformans
mpk1
yap1
Online Access:https://doi.org/10.1128/mSphere.00785-19

Internet

https://doi.org/10.1128/mSphere.00785-19

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