Gene Expression Profile Signature of Aggressive Waldenström Macroglobulinemia with Chromosome 6q Deletion

Background. Waldenström macroglobulinemia (WM) is a rare, indolent B-cell lymphoma. Clinically, chromosome 6q deletion (6q del) including loss of the B lymphocyte-induced maturation protein 1 gene (BLIMP-1) is reported to be associated with poor prognosis. However, it remains unclear how the underly...

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Bibliographic Details
Main Authors: Naohiro Sekiguchi, Junko Nomoto, Akihisa Nagata, Masahiro Kiyota, Ichiro Fukuda, Kazuaki Yamada, Naoki Takezako, Yukio Kobayashi
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/6728128