Engineering transcription factor-based biosensors for repressive regulation through transcriptional deactivation design in Saccharomyces cerevisiae

Abstract Background With the development of engineering the microbial cell factories, biosensors have been used widely for regulation of cellular metabolism and high-throughput screening. However, most of the biosensors constructed in Saccharomyces cerevisiae are designed for transcriptional activat...

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Bibliographic Details
Main Authors: Chenxi Qiu, Xiaoxu Chen, Reheman Rexida, Yu Shen, Qingsheng Qi, Xiaoming Bao, Jin Hou
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-020-01405-1