Age-dependent effects of UCP2 deficiency on experimental acute pancreatitis in mice.

Reactive oxygen species (ROS) have been implicated in the pathogenesis of acute pancreatitis (AP) for many years but experimental evidence is still limited. Uncoupling protein 2 (UCP2)-deficient mice are an accepted model of age-related oxidative stress. Here, we have analysed how UCP2 deficiency af...

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Bibliographic Details
Main Authors: Sarah Müller, Hannah Kaiser, Burkhard Krüger, Brit Fitzner, Falko Lange, Cristin N Bock, Horst Nizze, Saleh M Ibrahim, Georg Fuellen, Olaf Wolkenhauer, Robert Jaster
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3983280?pdf=render