Myeloid Cell Arg1 Inhibits Control of Arthritogenic Alphavirus Infection by Suppressing Antiviral T Cells.

Arthritogenic alphaviruses, including Ross River virus (RRV) and chikungunya virus (CHIKV), are responsible for explosive epidemics involving millions of cases. These mosquito-transmitted viruses cause inflammation and injury in skeletal muscle and joint tissues that results in debilitating pain. We...

Full description

Bibliographic Details
Main Authors: Kristina S Burrack, Jeslin J L Tan, Mary K McCarthy, Zhisheng Her, Jennifer N Berger, Lisa F P Ng, Thomas E Morrison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005191