Position-Dependent Influence of the Three Trp Residues on the Membrane Activity of the Antimicrobial Peptide, Tritrpticin

Position-Dependent Influence of the Three Trp Residues on the Membrane Activity of the Antimicrobial Peptide, Tritrpticin

Antimicrobial peptides (AMPs) constitute promising candidates for the development of new antibiotics. Among the ever-expanding family of AMPs, tritrpticin has strong antimicrobial activity against a broad range of pathogens. This 13-residue peptide has an unusual amino acid sequence that is almost...

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Bibliographic Details
Main Authors: Mauricio Arias, Leonard T. Nguyen, Andrea M. Kuczynski, Tore Lejon, Hans J. Vogel
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Antibiotics
Subjects:
antimicrobial peptides
tritrpticin
membrane permeabilization
tryptophan
fluorescence spectroscopy
NMR spectroscopy
Online Access:http://www.mdpi.com/2079-6382/3/4/595

Internet

http://www.mdpi.com/2079-6382/3/4/595

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