lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis

lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis

Recently, the long noncoding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) was reported to be involved in the pathogenesis of several cancers, including human colorectal cancer (CRC). However, the molecular basis for cancer initiation, development, and progression remains unclear. In this...

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Bibliographic Details
Main Authors: Hailu Wu, Ming Wei, Xinglu Jiang, Jiacheng Tan, Wei Xu, Xiaobo Fan, Rui Zhang, Chenbo Ding, Fengfeng Zhao, Xiangyu Shao, Zhigang Zhang, Ruihua Shi, Weijia Zhang, Guoqiu Wu
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
PVT1
miR-16-5p
VEGFA
AKT
CRC
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120300974

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http://www.sciencedirect.com/science/article/pii/S2162253120300974

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