Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility.

Genome-wide association studies (GWAS) have been successful in finding associations between specific genetic variants and cancer susceptibility in human populations. These studies have identified a range of highly statistically significant associations between single nucleotide polymorphisms (SNPs)...

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Bibliographic Details
Main Authors: Jesus Perez-Losada, Di Wu, Reyno DelRosario, Allan Balmain, Jian-Hua Mao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3278431?pdf=render