Naringenin Attenuates Non-Alcoholic Fatty Liver Disease by Enhancing Energy Expenditure and Regulating Autophagy via AMPK

Naringenin Attenuates Non-Alcoholic Fatty Liver Disease by Enhancing Energy Expenditure and Regulating Autophagy via AMPK

Background: The prevalence of non-alcoholic fatty liver disease (NAFLD) keeps growing recently.Purpose: To investigate the effects and mechanisms of naringenin (NAR) on NAFLD.Methods: High-fat diet (HFD)-induced NAFLD rats were orally administered with NAR at 10, 30, and 90 mg/kg for 2 weeks. The se...

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Bibliographic Details
Main Authors: Ying Yang, Yue Wu, Jie Zou, Yu-Hao Wang, Meng-Xia Xu, Wei Huang, Dao-Jiang Yu, Li Zhang, Yuan-Yuan Zhang, Xiao-Dong Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
non-alcoholic fatty liver disease
naringenin
energy expenditure
autophagy
mitochondrial biogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.687095/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.687095/full

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