Impaired expression of NADH dehydrogenase subunit 1 and PPARγ coactivator-1 in skeletal muscle of ZDF rats

Type 2 diabetes has been related to a decrease of mitochondrial DNA (mtDNA) content. In this study, we show increased expression of the peroxisome proliferator-activated receptor-α (PPARα) and its target genes involved in fatty acid metabolism in skeletal muscle of Zucker Diabetic Fatty (ZDF) (fa/fa...

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Bibliographic Details
Main Authors: Mireia Jové, Joel Salla, Anna Planavila, Àgatha Cabrero, Liliane Michalik, Walter Wahli, Juan C. Laguna, Manuel Vázquez-Carrera
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520319271