Aging Donor-Derived Human Mesenchymal Stem Cells Exhibit Reduced Reactive Oxygen Species Loads and Increased Differentiation Potential Following Serial Expansion on a PEG-PCL Copolymer Substrate

Aging Donor-Derived Human Mesenchymal Stem Cells Exhibit Reduced Reactive Oxygen Species Loads and Increased Differentiation Potential Following Serial Expansion on a PEG-PCL Copolymer Substrate

Human mesenchymal stem cells (hMSCs) have been widely studied for therapeutic development in tissue engineering and regenerative medicine. They can be harvested from human donors via tissue biopsies, such as bone marrow aspiration, and cultured to reach clinically relevant cell numbers. However, an...

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Bibliographic Details
Main Authors: Daniel A. Balikov, Spencer W. Crowder, Jung Bok Lee, Yunki Lee, Ung Hyun Ko, Mi-Lan Kang, Won Shik Kim, Jennifer H. Shin, Hak-Joon Sung
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
biomaterial
copolymer
stem cell
regenerative medicine
cell culture
Online Access:http://www.mdpi.com/1422-0067/19/2/359

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http://www.mdpi.com/1422-0067/19/2/359

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