FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans.

The fumarylacetoacetate hydrolase (FAH) protein superfamily of metabolic enzymes comprises a diverse set of enzymatic functions, including ß-diketone hydrolases, decarboxylases, and isomerases. Of note, the FAH superfamily includes many prokaryotic members with very distinct functions that lack homo...

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Main Authors: Andrea Taferner, Haymo Pircher, Rafal Koziel, Susanne von Grafenstein, Giorgia Baraldo, Konstantinos Palikaras, Klaus R Liedl, Nektarios Tavernarakis, Pidder Jansen-Dürr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4534308?pdf=render