SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization

SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization

Several lncRNAs have been linked to cancer. Here, the authors identify SNHG5 as a long non-coding RNA promoting proliferation and survival of colorectal cancer cells by protecting specific mRNAs from STAU1-mediated degradation.

Bibliographic Details
Main Authors: Nkerorema Djodji Damas, Michela Marcatti, Christophe Côme, Lise Lotte Christensen, Morten Muhlig Nielsen, Roland Baumgartner, Helene Maria Gylling, Giulia Maglieri, Carsten Friis Rundsten, Stefan E. Seemann, Nicolas Rapin, Simon Thézenas, Søren Vang, Torben Ørntoft, Claus Lindbjerg Andersen, Jakob Skou Pedersen, Anders H. Lund
Format: Article
Language:English
Published: Nature Publishing Group 2016-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13875

Internet

https://doi.org/10.1038/ncomms13875

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