Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle

Objective: The development of skeletal muscle insulin resistance is an early physiological defect, yet the intracellular mechanisms accounting for this metabolic defect remained unresolved. Here, we have examined the role of glucose-6-phosphate dehydrogenase (G6PDH) activity in the pathogenesis of i...

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Bibliographic Details
Main Authors: Robert S. Lee-Young, Nolan J. Hoffman, Kate T. Murphy, Darren C. Henstridge, Dorit Samocha-Bonet, Andrew L. Siebel, Peter Iliades, Borivoj Zivanovic, Yet H. Hong, Timothy D. Colgan, Michael J. Kraakman, Clinton R. Bruce, Paul Gregorevic, Glenn K. McConell, Gordon S. Lynch, Grant R. Drummond, Bronwyn A. Kingwell, Jerry R. Greenfield, Mark A. Febbraio
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816301338