Maternal LAMP/p55gagHIV-1 DNA immunization induces in utero priming and a long-lasting immune response in vaccinated neonates.

Maternal LAMP/p55gagHIV-1 DNA immunization induces in utero priming and a long-lasting immune response in vaccinated neonates.

Infants born to HIV-infected mothers are at high risk of becoming infected during gestation or the breastfeeding period. A search is thus warranted for vaccine formulations that will prevent mother-to-child HIV transmission. The LAMP/gag DNA chimeric vaccine encodes the HIV-1 p55gag fused to the lys...

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Bibliographic Details
Main Authors: Paula Ordonhez Rigato, Milton Maciel, Adriana Letícia Goldoni, Orlando Guerra Piubelli, Noemia Mie Orii, Ernesto Torres Marques, Joseph Thomas August, Alberto José da Silva Duarte, Maria Notomi Sato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3280311?pdf=render

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http://europepmc.org/articles/PMC3280311?pdf=render

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