Integrated Modeling of GC-Content, Mappability, Tumor Impurity and Aneuploidy for Accurate Detection of Genomic Aberrations
Next-generation sequencing has been widely used in cancer-focused studies for comprehensive landscape of tumor genomes. Detection of genomic aberrations is one of the focal points in this area. Analysis of tumor sequencing data is usually complicated by several critical issues, such as GC-content bi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IEEE
2018-01-01
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| Series: | IEEE Access |
| Subjects: | |
| Online Access: | https://ieeexplore.ieee.org/document/8502207/ |