Syncytiotrophoblast derived extracellular vesicles transfer functional placental miRNAs to primary human endothelial cells

Abstract During the pregnancy associated syndrome preeclampsia (PE), there is increased release of placental syncytiotrophoblast extracellular vesicles (STBEVs) and free foetal haemoglobin (HbF) into the maternal circulation. In the present study we investigated the uptake of normal and PE STBEVs by...

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Bibliographic Details
Main Authors: Tina Cronqvist, Dionne Tannetta, Matthias Mörgelin, Mattias Belting, Ian Sargent, Mary Familari, Stefan R. Hansson
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04468-0