The critical role of IL-34 in osteoclastogenesis.

It has been widely believed that the cytokines required for osteoclast formation are M-CSF (also known as CSF-1) and RANKL. Recently, a novel cytokine, designated IL-34, has been identified as another ligand of CSF1R. This study was to explore the biological function, specifically osteoclastogenesis...

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Bibliographic Details
Main Authors: Zhi Chen, Kalman Buki, Jukka Vääräniemi, Guoliang Gu, H Kalervo Väänänen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3072988?pdf=render