Mobile genetic element-encoded cytolysin connects virulence to methicillin resistance in MRSA.

Bacterial virulence and antibiotic resistance have a significant influence on disease severity and treatment options during bacterial infections. Frequently, the underlying genetic determinants are encoded on mobile genetic elements (MGEs). In the leading human pathogen Staphylococcus aureus, MGEs t...

Full description

Bibliographic Details
Main Authors: Shu Y Queck, Burhan A Khan, Rong Wang, Thanh-Huy L Bach, Dorothee Kretschmer, Liang Chen, Barry N Kreiswirth, Andreas Peschel, Frank R Deleo, Michael Otto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2712073?pdf=render