Targeted Gene Delivery into the Mammalian Inner Ear Using Synthetic Serotypes of Adeno-Associated Virus Vectors

Targeting specific cell types in the mammalian inner ear is important for treating genetic hearing loss due to the different cell type-specific functions. Adeno-associated virus (AAV) is an efficient in vivo gene transfer vector, and it has demonstrated promise for treating genetic hearing loss. Alt...

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Bibliographic Details
Main Authors: Min-A Kim, Nari Ryu, Hye-Min Kim, Ye-Ri Kim, Byeonghyeon Lee, Tae-Jun Kwon, Jinwoong Bok, Un-Kyung Kim
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050119300051