New World feline APOBEC3 potently controls inter-genus lentiviral transmission

New World feline APOBEC3 potently controls inter-genus lentiviral transmission

Abstract Background The apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) gene family appears only in mammalian genomes. Some A3 proteins can be incorporated into progeny virions and inhibit lentiviral replication. In turn, the lentiviral viral infectivity factor (Vif)...

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Bibliographic Details
Main Authors: Yoriyuki Konno, Shumpei Nagaoka, Izumi Kimura, Keisuke Yamamoto, Yumiko Kagawa, Ryuichi Kumata, Hirofumi Aso, Mahoko Takahashi Ueda, So Nakagawa, Tomoko Kobayashi, Yoshio Koyanagi, Kei Sato
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Retrovirology
Subjects:
Lentivirus
FIV
APOBEC3
Vif
Evolutionary arms race
Puma
Online Access:http://link.springer.com/article/10.1186/s12977-018-0414-5

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