CGRP Is Critical for Hot Flushes in Ovariectomized Mice

CGRP Is Critical for Hot Flushes in Ovariectomized Mice

Hot flushes are common and troublesome symptoms of menopause. The neuropeptide calcitonin gene-related peptide (CGRP) is increased in plasma during hot flushes but it has not been clear if CGRP is causally involved in the mechanism underpinning the flushes. Here, we examined the effect of interventi...

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Bibliographic Details
Main Authors: Daniel B. Wilhelms, Hua Dock, Haissa O. Brito, Emma Pettersson, Andrea Stojakovic, Joanna Zajdel, David Engblom, Elvar Theodorsson, Mats L. Hammar, Anna-Clara E. Spetz Holm
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
calcitonin gene-related peptide
antagonist
thermoregulation
hot flushes
mice
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01452/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01452/full

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