Multiple advantageous amino acid variants in the NAT2 gene in human populations.

Multiple advantageous amino acid variants in the NAT2 gene in human populations.

BACKGROUND: Genetic variation at NAT2 has been long recognized as the cause of differential ability to metabolize a wide variety of drugs of therapeutic use. Here, we explore the pattern of genetic variation in 12 human populations that significantly extend the geographic range and resolution of pre...

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Main Authors: Francesca Luca, Giuseppina Bubba, Massimo Basile, Radim Brdicka, Emmanuel Michalodimitrakis, Olga Rickards, Galina Vershubsky, Lluis Quintana-Murci, Andrey I Kozlov, Andrea Novelletto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2527519?pdf=render

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http://europepmc.org/articles/PMC2527519?pdf=render

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