Adverse maternal environment and western diet impairs cognitive function and alters hippocampal glucocorticoid receptor promoter methylation in male mice
Abstract Adverse maternal environment (AME) and high‐fat diet in early childhood increase the risk of cognitive impairment and depression later in life. Cognitive impairment associates with hippocampal dysfunction. A key regulator of hippocampal function is the glucocorticoid receptor. Increased hip...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-04-01
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Series: | Physiological Reports |
Subjects: | |
Online Access: | https://doi.org/10.14814/phy2.14407 |