Low-dose endosulfan inhibits proliferation and induces senescence and pro-inflammatory cytokine production in human lymphocytes, preferentially impacting cytotoxic cells

Low-dose endosulfan inhibits proliferation and induces senescence and pro-inflammatory cytokine production in human lymphocytes, preferentially impacting cytotoxic cells

Endosulfan is a DDT-era organochlorine pesticide. Due to past and current environmental contamination, investigation of endosulfan exposure is of current importance. Acute high dose exposure precipitates neural/endocrine system damage, but the effects on the immune system and of lower doses are not...

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Bibliographic Details
Main Authors: Martha Cecilia Téllez-Bañuelos, Salvador González-Ochoa, Pablo Cesar Ortiz-Lazareno, Vida Celeste Rosas-Gonzalez, Jaime Gómez-Villela, Jesse Haramati
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Immunotoxicology
Subjects:
endosulfan
organochlorine pesticide
nk cells
cytotoxic cells
senescence
interferon
pbmc
immunosenescence
Online Access:http://dx.doi.org/10.1080/1547691X.2019.1668513

Internet

http://dx.doi.org/10.1080/1547691X.2019.1668513

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