Impaired Barrier Function and Autoantibody Generation in Malnutrition Enteropathy in Zambia

Impaired Barrier Function and Autoantibody Generation in Malnutrition Enteropathy in Zambia

Intestinal damage in malnutrition constitutes a threat to the survival of many thousands of children globally. We studied children in Lusaka, Zambia, with severe acute malnutrition (SAM) and persistent diarrhea using endoscopy, biopsy and analysis of markers and protective proteins in blood and inte...

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Bibliographic Details
Main Authors: Beatrice Amadi, Ellen Besa, Kanekwa Zyambo, Patrick Kaonga, John Louis-Auguste, Kanta Chandwe, Phillip I. Tarr, Donna M. Denno, James P. Nataro, William Faubion, Anne Sailer, Sunil Yeruva, Tricia Brantner, Joseph Murray, Andrew J. Prendergast, Jerrold R. Turner, Paul Kelly
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:EBioMedicine
Subjects:
Enteropathy
Environmental enteric dysfunction
HIV
Malnutrition
Glucagon-like peptide 2
Microbial translocation
Autoantibodies
Tissue transglutaminase serology, deamidated gliadin peptide serology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417302906

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http://www.sciencedirect.com/science/article/pii/S2352396417302906

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