Non-Desmoglein Antibodies in Patients With Pemphigus Vulgaris

Non-Desmoglein Antibodies in Patients With Pemphigus Vulgaris

Pemphigus vulgaris (PV) is a potentially life-threatening mucocutaneous autoimmune blistering disease. Patients develop non-healing erosions and blisters due to cell–cell detachment of keratinocytes (acantholysis), with subsequent suprabasal intraepidermal splitting. Identified almost 30 years ago,...

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Bibliographic Details
Main Authors: Kyle T. Amber, Manuel Valdebran, Sergei A. Grando
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
pemphigus
autoantibodies
secretory pathway Ca2+ ATPase
ATP2C1
acantholysis
keratinocyte
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01190/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01190/full

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