The Role of Microglia and Matrix Metalloproteinases Involvement in Neuroinflammation and Gliomas

Matrix metalloproteinases (MMPs) are involved in the pathogenesis of neuroinflammatory diseases (such as multiple sclerosis) as well as in the expansion of malignant gliomas because they facilitate penetration of anatomical barriers (such as the glia limitans) and migration within the neuropil. This...

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Bibliographic Details
Main Authors: Helen Könnecke, Ingo Bechmann
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2013/914104