Factors That Improve RT-QuIC Detection of Prion Seeding Activity

Factors That Improve RT-QuIC Detection of Prion Seeding Activity

Rapid and sensitive detection of prions is important in managing prion diseases. The real-time quaking-induced conversion (RT-QuIC) assay for prion seeding activity has been applied to many prion diseases and provides for specific antemortem diagnostic testing. We evaluated RT-QuIC’s long-term consi...

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Bibliographic Details
Main Authors: Christina D. Orrú, Andrew G. Hughson, Bradley R. Groveman, Katrina J. Campbell, Kelsie J. Anson, Matteo Manca, Allison Kraus, Byron Caughey
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Viruses
Subjects:
prion
CJD
olfactory mucosa
RT-QuIC
scrapie
CWD
BSE
Online Access:http://www.mdpi.com/1999-4915/8/5/140

Internet

http://www.mdpi.com/1999-4915/8/5/140

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