Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties.

The cancer stem cell theory hypothesizes that cancers are perpetuated by cancer stem cells (CSC) or tumor initiating cells (TIC) possessing self-renewal and other stem cell-like properties while differentiated non-stem/initiating cells have a finite life span. To investigate whether the hypothesis i...

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Bibliographic Details
Main Authors: Elaine Lai-Han Leung, Ronald R Fiscus, James W Tung, Vicky Pui-Chi Tin, Lik Cheung Cheng, Alan Dart-Loon Sihoe, Louis M Fink, Yupo Ma, Maria Pik Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2988826?pdf=render