Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype

<p>Abstract</p> <p>Background</p> <p>A major feature of chronic obstructive pulmonary disease (COPD) is airway remodelling, which includes an increased airway smooth muscle (ASM) mass. The mechanisms underlying ASM remodelling in COPD are currently unknown. We hypothesi...

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Bibliographic Details
Main Authors: Zaagsma Johan, Toorn Marco, Sami Riham, Lesterhuis Andries H, Gosens Reinoud, Pera Tonio, Meurs Herman
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/11/1/48