Combined use of bacterial artificial chromosomes-on-beads with karyotype detection improves prenatal diagnosis

Combined use of bacterial artificial chromosomes-on-beads with karyotype detection improves prenatal diagnosis

Abstract Background This study evaluated the individual and combined diagnostic performance of the bacterial artificial chromosomes (BACs)-on-Beads (BoBs™) assay and conventional karyotyping for the prenatal detection of chromosomal abnormalities in pregnant women who were 35 or more years-old. Meth...

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Bibliographic Details
Main Authors: Zhengyou Miao, Xia Liu, Furong Hu, Ming Zhang, Pingli Yang, Luming Wang
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Molecular Cytogenetics
Subjects:
Karyotyping
Prenatal diagnosis
Chromosome disorders
Chromosome aberrations
Online Access:http://link.springer.com/article/10.1186/s13039-019-0416-6

Internet

http://link.springer.com/article/10.1186/s13039-019-0416-6

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