Immunoglobulin G responses against falciparum malaria specific antigens are higher in children with homozygous sickle cell trait than those with normal hemoglobin

Immunoglobulin G responses against falciparum malaria specific antigens are higher in children with homozygous sickle cell trait than those with normal hemoglobin

Abstract Background High Immunoglobulin G (IgG) response to Plasmodium falciparum antigens is associated with partial malaria protection in sickle hemoglobin (HbS) children. However, this response has been more studied in children with heterozygous sickle cell trait (HbAS) but little explored in tho...

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Bibliographic Details
Main Authors: George Msema Bwire, Mtebe Majigo, Robert Makalla, Lillian Nkinda, Akili Mawazo, Mucho Mizinduko, Julie Makani
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Immunology
Subjects:
ELISA
Children
Dar Es Salaam
Plasmodium falciparum
Immunoglobulin G
Sickle cell
Online Access:http://link.springer.com/article/10.1186/s12865-019-0294-z

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http://link.springer.com/article/10.1186/s12865-019-0294-z

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