Lipid imaging for visualizing cilastatin amelioration of cisplatin-induced nephrotoxicity

Lipid imaging for visualizing cilastatin amelioration of cisplatin-induced nephrotoxicity

Nephrotoxicity is a major limitation to cisplatin antitumor therapies. Cilastatin, an inhibitor of renal dehydropeptidase-I, was recently proposed as a promising nephroprotector against cisplatin toxicity, preventing apoptotic cell death. In this work, cilastatin nephroprotection was further investi...

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Bibliographic Details
Main Authors: Estefanía Moreno-Gordaliza, Diego Esteban-Fernández, Alberto Lázaro, Sarah Aboulmagd, Blanca Humanes, Alberto Tejedor, Michael W. Linscheid, M. Milagros Gómez-Gómez
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Journal of Lipid Research
Subjects:
mass spectrometry
kidney
cancer
renal disease
molecular imaging
nephroprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520335264

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http://www.sciencedirect.com/science/article/pii/S0022227520335264

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