Prokineticin 1–prokineticin receptor 1 signaling in trophoblast promotes embryo implantation and placenta development

Abstract Successful pregnancy establishment in mammals depends on proper embryo-maternal communication. Prokineticin 1 (PROK1) is a secretory protein that exerts pleiotropic functions in various tissues. Despite the studies that have primarily been performed with human cell lines and mice, the funct...

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Bibliographic Details
Main Authors: Ewelina Goryszewska-Szczurek, Monika Baryla, Piotr Kaczynski, Agnieszka Waclawik
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93102-1