Constitutive nitric oxide synthase (cNOS) activity in Langerhans islets from streptozotocin diabetic rats

Nitric oxide synthase activity was measured in Langerhans islets isolated from control and streptozotocin diabetic rats. The activity of the enzyme was linear up to 150 µg of protein from control rats and was optimal at 0.1 µM calcium, when it was measured after 45 min of incubation at 37oC in the p...

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Bibliographic Details
Main Authors: T.M. Fonovich de Schroeder, M.D. Carattino, M. Frontera, O.L. Catanzaro
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1998-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000500004