Paclitaxel induces Stathmin 1 phosphorylation, microtubule stability and apoptosis in acute lymphoblastic leukemia cells

Paclitaxel induces Stathmin 1 phosphorylation, microtubule stability and apoptosis in acute lymphoblastic leukemia cells

Acute lymphoblastic leukemia (ALL) is a hematological malignancy characterized by abnormal proliferation and accumulation of lymphoblasts in the hematopoietic system. Stathmin 1 is a proliferation marker for normal lymphocytes, which has been described as highly expressed in ALL patients and functio...

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Bibliographic Details
Main Authors: João Agostinho Machado-Neto, Ana Paula Nunes Rodrigues Alves, Jaqueline Cristina Fernandes, Juan Luiz Coelho-Silva, Renata Scopim-Ribeiro, Bruna Alves Fenerich, Fernanda Borges da Silva, Priscila Santos Scheucher, Belinda Pinto Simões, Eduardo Magalhães Rego, Fabiola Traina
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Heliyon
Subjects:
Medicine
Oncology
Cancer research
Pharmaceutical science
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844017314664

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http://www.sciencedirect.com/science/article/pii/S2405844017314664

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