Heme oxygenase-1 accelerates cutaneous wound healing in mice.

Heme oxygenase-1 (HO-1), a cytoprotective, pro-angiogenic and anti-inflammatory enzyme, is strongly induced in injured tissues. Our aim was to clarify its role in cutaneous wound healing. In wild type mice, maximal expression of HO-1 in the skin was observed on the 2(nd) and 3(rd) days after woundin...

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Main Authors: Anna Grochot-Przeczek, Radoslaw Lach, Jacek Mis, Klaudia Skrzypek, Malgorzata Gozdecka, Patrycja Sroczynska, Milena Dubiel, Andrzej Rutkowski, Magdalena Kozakowska, Anna Zagorska, Jacek Walczynski, Halina Was, Jerzy Kotlinowski, Justyna Drukala, Krzysztof Kurowski, Claudine Kieda, Yann Herault, Jozef Dulak, Alicja Jozkowicz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2686151?pdf=render