The role of pruriceptors in enhancing sensitivity to pruritogens in a murine chronic compression model of dorsal root ganglion

Abstract Chronic pruritus is a symptom that commonly observed in neurological diseases. It has been hypothesized that the chronic pruritus may result from sensitization of itch-signaling pathways but the mechanisms remain obscure. In this study, we established a mouse model of chronic compression of...

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Bibliographic Details
Main Authors: Tao Wang, Jin Tao, Yehong Fang, Chao Ma
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-021-00730-9