Genome-wide association study of irritable vs. elated mania suggests genetic differences between clinical subtypes of bipolar disorder.

The use of clinical features to define subtypes of a disorder may aid in gene identification for complex diseases. In particular, clinical subtypes of mania may distinguish phenotypic subgroups of bipolar subjects that may also differ genetically. To assess this possibility, we performed a genome-wi...

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Bibliographic Details
Main Authors: Tiffany A Greenwood, Bipolar Genome Study (BiGS) Consortium, John R Kelsoe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23326512/?tool=EBI