Low T-Cell Responses to Mitogen Stimulation Predicts Poor Survival in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation

Low T-Cell Responses to Mitogen Stimulation Predicts Poor Survival in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation

BackgroundSuccessful engraftment and reconstitution of the innate and adaptive immune system are associated with improved outcomes in recipients of allogeneic hematopoietic stem cell transplantation (HSCT). A clinically meaningful and simple biomarker of immunosuppression could potentially assist cl...

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Bibliographic Details
Main Authors: Michelle K. Yong, Paul U. Cameron, Monica A. Slavin, Allen C. Cheng, C. Orla Morrissey, Krystal Bergin, Andrew Spencer, David Ritchie, Sharon R. Lewin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
mitogen
biomarker
T-cell immunity
hematopoietic stem cell transplantation
mortality
prognosis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01506/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01506/full

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